Rapid progress in genetic research plus the fact that most of the patients with congenital heart disease now survive and reach their reproductive age both emphasize the urgent need for intensive genetic research. This requires large numbers of patients and data, only to be achieved by a longterm, project transcendent approach.
Data entry of patients under treatment at non-academic hospitals was started in 2004. At present more than 17.000 patients from 102 hospitals have been included. Over 5900 of these patients’ blood samples for DNA analysis have been collected.